Splice Trailer Best Movies Ever Best movies ever he sci-fi thriller Splice stars Adrien Brody and Sarah Polley as superstar genetic engineers Clive and Elsa, who specialize in splicing together DNA from different animals to create incredible new hybrids. Now they want to use human DNA in a hybrid that could revolutionize science and medicine. But when the pharmaceutical company that funds their research forbids it, Clive and Elsa secretly conduct their own experiments. The result is Dren
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